Anchorage Digital Ventures: Request for Startups

Anchorage Digital Ventures (ADV) is writing strategic checks to early-stage teams building the next generation of institutional-grade crypto infrastructure.

We back founders building the rails that make crypto seamless, capital-efficient, and secure for the world's largest allocators.

Submit at anchorage.com/ventures 

Onchain Derivatives, Prime Brokerage & Market Structure

Institutional capital is moving onchain. We're looking for teams building the infrastructure that makes that transition seamless, capital-efficient, and trustless.

  • Execution & Funding Separation: Prime brokerage layers and margin networks that fundamentally separate the execution of a trade from the funding of a trade, unlocking capital efficiency across venues.
  • High-Performance DeFi Primitives: Capital-efficient DeFi protocols built directly on high-performance networks, leveraging sub-second finality and deep native liquidity.
  • Perp DEX Tooling & Infrastructure: Infrastructure bridging institutional capital to decentralized perpetual futures markets, including smart routing, composable risk layers, and advanced strategy unlocks (like intramarket carry trades).
  • Onchain 0DTE & Exotic Options: Protocols bringing zero-days-to-expiration (0DTE) options and structured products onchain with deep liquidity and institutional-grade execution.
  • Basis Trade & Yield Strategies: Automated vaults and strategies that execute basis trades and delta-neutral yield farming across perpetual DEXs.

Stablecoins, FinFra & The GENIUS Act Era

Regulatory clarity is arriving. The teams that build the compliant fiat and crypto rails now will define the next decade of global B2B settlement.

  • Regulated B2B2x Platforms & FinFra: Scalable payment orchestration layers offering a complete, compliant fiat-to-crypto rail stack that bridges traditional B2B workflows with digital asset settlement.
  • Bank-Grade Stablecoin Issuance: Infrastructure that helps traditional banks and financial institutions issue and manage stablecoins in compliance with the GENIUS Act.
  • Global Routing & FX Engines: Infrastructure leveraging stablecoins for FX routing, cross-border corporate treasury management, and instant settlement in emerging markets.
  • Programmable Settlement Rails: Systems that upgrade legacy banking ledgers using stablecoins and tokenized deposits for instant, cross-border institutional settlement.

Asset Tokenization & Institutional DeFi Bringing traditional financial primitives onchain requires secure, compliant, and composable infrastructure tailored to institutional risk profiles.

  • Risk Tranching & Yield Segmentation: Smart contracts that segment volatile crypto-native yields, allowing allocators to access tailored risk profiles (e.g., principal-protected senior tranches or leveraged junior tranches).
  • Regulated Yield Wrappers: Marketplaces and infrastructure providers offering turnkey, compliant structures (like SMAs) for asset managers to distribute institutional-grade strategies natively on-chain.
  • Capital-Efficient RWAs: Synthetic RWA protocols and derivatives moving beyond standard AMM pools to offer instant redeemability, deep liquidity, and composability for institutional market makers.

AI Agents, Compute & The Autonomous Economy

The intersection of AI and crypto is one of the most important frontiers in technology. We’re seeing infrastructure emerge that allows institutions to access this space more safely.

  • Heavy-Asset Financing & DePIN: Platforms underwriting physical hardware (e.g., AI GPUs) and structuring the cash flows into tradable, yield-bearing financial products for institutional investors.
  • Agentic Wallets & KYA (Know Your Agent): Infrastructure that allows AI agents to securely hold funds, execute trades, and build verifiable onchain reputations and credit scores.
  • Agent-to-Agent Settlement Rails: Protocols designed for machine-to-machine micropayments, enabling agents to pay for API calls, compute, and data instantly and permissionlessly.
  • AI-Driven DeFi Co-pilots: Autonomous agents that actively manage institutional portfolios, execute complex routing strategies, and optimize yield across fragmented markets.
  • Verifiable Agent Logic: Frameworks using TEEs or ZKPs to prove that an AI agent executed a specific model without tampering.

Prediction Markets & Information Finance

We see prediction markets evolving from retail novelty to institutional-grade risk infrastructure. We back teams making that leap real.

  • Event Derivative Infrastructure: Foundational tooling that transitions prediction venues into mature financial networks—including cross-venue aggregators, advanced order routing, and specialized clearinghouses.
  • Prediction Market Credit Layers: Protocols that solve the capital inefficiency of prediction markets by utilizing underlying mathematical invariants (e.g., fully hedged outcome baskets) to offer delta-neutral yield for lenders and capital-efficient leverage for traders.
  • AI Oracles & Event Resolution: Decentralized oracle networks that leverage LLMs and autonomous agents to accurately and securely resolve complex, long-tail markets without subjective human intervention.
  • B2B Information Finance: Platforms allowing traditional corporations and asset managers to hedge against highly specific operational, supply chain, or geopolitical risks natively onchain.

Privacy & Institutional Security

Institutions require privacy-preserving infrastructure that doesn't sacrifice transparency or compliance. We back the teams solving this core tension.

  • Secrets-as-a-Service: Infrastructure providing programmable data access rules, client-side encryption, and decentralized key management for institutional onchain data.
  • ZK-Powered Compliance: Zero-knowledge proof systems allowing institutions to prove KYC/AML compliance or reserve adequacy without revealing sensitive metadata.
  • Spec-is-Law Security: Advanced formal verification tools and runtime monitoring systems that enforce global invariants and automatically block malicious transactions.

Why Build With Anchorage Digital Ventures?

Beyond capital, ADV-backed protocols gain access to the full Anchorage Digital platform - including:

  • Fiat banking & capital introduction: From day one, ADV portfolio companies get access to Anchorage Digital's fiat banking rails, so you know where to deposit the check. Beyond that, we actively make introductions to co-investors and strategic capital sources to help you complete your round.
  • Institutional readiness from day one: Our dedicated team provides 1:1 guidance on technical architecture and go-to-market strategy, so you show up to institutional conversations with credibility already built in.
  • Custody & Early Asset Support: Anchorage Digital supports the broadest asset portfolio of any institutional custodian. With our Crypto VC clients holding nearly 175 distinctive assets, we are uniquely equipped to provide the early asset listings critical to your token launch.
  • Institutional Distribution & Porto: We actively seek products that can act as alternative yield engines for our institutional clients. If you build high-quality structured products, Anchorage Digital provides the distribution network.
  • OES & Settlement: Access to off-exchange settlement capabilities and margin networks to seamlessly bridge secure custody and execution.
  • Staking & Yield: Anchorage Digital offers secure staking yield generation and DeFi protocol participation as core services for protocol-native clients.
  • Institutional Network: Immediate access to Anchorage Digital's network of institutional clients, VCs, asset managers, and market makers.
  • Get your asset in front of the world's leading institutions: Launching with Anchorage Digital means your asset is immediately accessible to the institutions that matter most, the exact allocators you're building for.

    If you are building in any of the following sectors, we want to hear from you:

How to Apply

Applications are reviewed on a rolling basis. To keep the process efficient and streamlined, all teams should apply directly through the landing page.

Submit Your Project

About Anchorage Digital

Anchorage Digital is a global crypto platform that enables institutions to participate in digital assets through trading, staking, custody, governance, settlement, stablecoin issuance, and the industry’s leading security infrastructure. Home to Anchorage Digital Bank N.A., the first federally chartered crypto bank in the U.S., Anchorage Digital also serves institutions through Anchorage Digital Singapore, which is licensed by the Monetary Authority of Singapore; Anchorage Digital NY, which holds a BitLicense from the New York Department of Financial Services; and self-custody wallet Porto by Anchorage Digital. Anchorage Digital Bank also offers fiat custody services through the use of an FDIC-insured, licensed sub-custodian. Anchorage Digital is funded by leading institutions including Andreessen Horowitz, GIC, Goldman Sachs, KKR, and Visa, with a valuation of $4.2 billion. Founded in 2017 in San Francisco, California, Anchorage Digital has offices in New York, New York; Porto, Portugal; Singapore; and Sioux Falls, South Dakota. Learn more at anchorage.com, on X @Anchorage, and on LinkedIn.

This post is intended for informational purposes only. It is not to be construed as and does not constitute an offer to sell or a solicitation of an offer to purchase any securities in Anchor Labs, Inc., or any of its subsidiaries, and should not be relied upon to make any investment decisions. Furthermore, nothing within this announcement is intended to provide tax, legal, or investment advice and its contents should not be construed as a recommendation to buy, sell, or hold any security or digital asset or to engage in any transaction therein.

Anchorage Digital Bank National Association offers fiat custody services through the use of an FDIC-insured, licensed sub-custodian.

Additional reading

Anchorage Digital’s Comment Letter on OCC’s NPRM for GENIUS Act
Anchorage Digital and M0 Partner to Power the Next Wave of Stablecoin Builders
Anchorage Digital Allows Institutional Access to MEGA from Day One
Anchorage Digital Enables Institutional Solana Staking with Marinade Finance
Anchorage Digital and the Republic of Marshall Islands Are Redefining Sovereign Finance Onchain
Anchorage Digital Becomes Day-One Launch Partner for Mezo’s Token Generation Event